A Case of Rhinogenic Intracranial Complication: Epidural Abscess

We report a case of acute rhinosinusitis complicated by epidural abscess. A 33-year-old woman consulted her local otorhinolaryngology clinic complaining of left eye pain and left periorbital swelling. After visiting additional clinics and receiving treatment she did not obtain relief from her symptoms. Thereafter, she was referred to our hospital. Contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI) were conducted and it was found that acute rhinosinusitis had caused an epidural abscess in the left frontal tip. The patient was admitted to the hospital and endoscopic sinus surgery (ESS) as well as septoplasty were performed under general anesthesia. A neurosurgeon was consulted regarding the brain lesion and treatment with antibiotics was selected. Intravenous PAPM/BP (panipenem/betamipron) and hydrocortisone sodium succinate were administered postoperatively. On the fifth postoperative day, the patient\u27s condition had improved and the nasal inflammation had almost disappeared. She was discharged from hospital on the tenth postoperative day

Menelloides C and D, New Sesquiterpenoids from the Gorgonian Coral Menella sp

Two new metabolites, including a lindenane-type sesquiterpenoid, menelloide C (1), and a germacrane-type sesquiterpenoid, menelloide D (2), were isolated from a Formosan gorgonian coral identified as Menella sp. The structures of 1 and 2 were established by spectroscopic methods and 2 displayed a weak inhibitory effect on the release of elastase by human neutrophils